APHAR - Austrian Pharmacological Society - Österreichische Pharmakologische Gesellschaft

General
Information THURSDAY
23 Nov FRIDAY
24 Nov SATURDAY
25 Nov POSTERS
23–25 Nov

12th Scientific Symposium
of the Austrian Pharmacological Society (APHAR)
Joint Meeting with the Austrian Society of Toxicology (ASTOX)
POSTER PRESENTATIONS
23–25 November

(→ Printversion)
(Preliminary program, subject to change)

POSTER Presentations

Posters will be on display for the entire period of the meeting (Thursday afternoon till Saturday noon). Presenting authors are requested to indicate their presence at their poster on the poster board (preferably during coffee breaks).
APHAR (Non-Clinical)

A7
A Site of Interaction between the Selectivity Filter and the Inner Vestibule of the Voltage-Gated Na⁺ Channel
Touran Zarrabi*, B. Latzenhofer, M. Mille, E. Zebedin, K. Hilber, H. Todt (Wien)

A9
Duramycin Effects on hERG Potassium and Voltage-Gated Sodium Currents: A QT-Prolongation Risk?
Eva Zebedin*, H. Pankevych, T. Zarrabi, B. Latzenhofer, M. Mille, H. Todt, M. Freissmuth, K. Hilber (Wien)

A10
Brain Lesions in Aortic Denervated vs. Sham-Operated Rats
Dimitrios Kouvelas*, E. Amaniti, Ch. Pourzitaki, D. Kapoukranidou, J. Kalpidis, D. Vasilakos (Thessaloniki)

A16
The Signaling Mute hCMV Chemokine Receptor US28R129A Prevents Melanoma Growth
Hannes Seidl*, H. Schaider, P. Quan, S. Frank, Z. Liu, M. Fukunaga, R. McDaid, H. Kerl, M. Herlyn, M. Waldhoer (Graz, Philadelphia)
APHAR (Clinical Section)

K1
No Immunomodulatory Effect of Fosfomycin in Experimental Endotoxemia in Humans
Robert Sauermann*, C. Marsik, I. Steiner, K. Seir, T. Cvitko, M. Zeitlinger, B. Jilma, C. Joukhadar (Wien)

K2
Intravenous Administration of Clonidine Reduces Intraocular Pressure and Alters Ocular Blood Flow
Günther Weigert*, H. Resch, A. Luksch, H.A. Reitsamer, G. Fuchsjäger-Mayrl, L. Schmetterer, G. Garhöfer (Wien)

K3
The Effects of Short Term Statin Pre-Treatment and Subsequent Low Dose Endotoxemia on Circulating Endothelial Progenitor Cells in Healthy Volunteers
Alexander O. Spiel*, F.B. Mayr, J.M. Leitner, C. Firbas, W. Sieghart, B. Jilma (Wien)

K6
Effects of the Specific Interleukin-8 Inhibitor Reparixin on Endotoxin-Induced Inflammation
Judith M. Leitner*, F.B. Mayr, A.O. Spiel, B. Steinlechner, B. Jilma (Wien)

K8
The Effects of Intravenous Histamine and Histamine Receptor Blockade on Ocular Blood Flow
Katharina Karl*, H. Resch, G. Weigert, L. Schmetterer, G. Garhöfer (Wien)

K11
MicroPET Imaging with the β-Amyloid Probe [¹⁸F]FDDNP in a Transgenic Mouse Model of Alzheimer's Disease
Oliver Langer*, C. Kuntner, T. Wanek, M. Bauer, M. Mandler, P. Angelberger, M. Müller, H. Kvaternik (Wien, Seibersdorf)
ASTOX

The presenters of ASTOX posters are requested to be present at their poster at the ASTOX Poster Session (Thursday 23 Nov, 13:30–14:00). Please make sure that you put up your poster before the session starts. The best ASTOX presentation (short communication or poster) will be selected to receive the Roche Prize (EUR 500), which will be awarded at the end of the Thursday afternoon session. Posters should remain on display throughout the entire meeting (i.e. until Saturday noon).

T1
Alkyl- and Aryl-Substituted Spin Traps: Free Radical Adduct Formation and Toxicity Studies
Klaus Stolze*, N. Rohr-Udilova, B. Marian, B. Grasl-Kraupp, H. Nohl (Wien)

T4
Alterations of the Ras Pathway in Hepatocarcinogenesis: Species Comparison and Implications for Risk Assessment
Doris Macheiner*, C. Rodgarkia-Dara, M. Grusch, H. Sutterlüty, W. Mikulits, H. Huber, R. Schulte-Hermann, B. Grasl-Kraupp (Wien)

T5
Linoleic Acid Hydroperoxides and the Induction of Antiapoptotic Genes in Cultured Hepatocarcinoma Cells
Nataliya Rohr-Udilova*, S. Sagmeister, K. Stolze, H. Nohl, R. Schulte-Hermann, B. Grasl-Kraupp (Wien)

T8
The Fusarium Toxin Enniatin Exerts Cytotoxic Activities via Apotosis Induction
Rita Dornetshuber*, P. Heffeter, R. Kamyar, W. Berger, R. Lemmens-Gruber (Wien)

T9
Impact of Staining Procedures on the Results of the Micronucleus Assay with Exfoliated Cells as Biomarkers for Human Cancer Risk
Armen Nersesyan*, M. Kundi, K. Atefie, R. Schulte-Hermann, S. Knasmüller (Wien)

L1
Hospital Waste Water: Health Risk for Human and Environment by Cytostatic Drug Emissions? Part I: Model Calculation and Chemical Monitoring
M. Fuerhacker, S.N. Mahnik, K. Lenz, N. Weissenbacher, R.M. Mader, P. Krenn, S. Hann, G. Koellensperger, M. Uhl, S. Knasmüller, F. Ferk, Wilfried Bursch* (Wien)

L2
Hospital Waste Water: Health Risk for Human and Environment by Cytostatic Drug Emissions? Part II: Biological Monitoring (Genotoxicity Assays) and Risk Assessment
F. Ferk, M. Uhl, M. Fuerhacker, S.N. Mahnik, K. Lenz, N. Weissenbacher, R.M. Mader, P. Krenn, S. Hann, G. Koellensperger, S. Knasmüller, Wilfried Bursch* (Wien)

L4
The Potential Antimutagenic and Antioxidant Effects of Maillard Reaction Products Used as "Natural Antibrowning" Agents
S. Reichhold, K. Koschtnig, Karl-Heinz Wagner* (Wien)

L6
Use of Human-Derived Cell Lines for the Investigation of Dietary Factors which Affect DNA Stability
Heike Winter*, B. Grasl-Kraupp, R. Schulte-Hermann, M. Grusch, W. Mikulits, V. Ehrlich, S. Knasmüller (Wien)

L7
DIMBOA and DIBOA, Two Naturally Occuring Benzoxazinoides, Cause Aneuploidy in a Human-Derived Liver Cell Line (HepG2)
Christoph Buchmann*, A. Nersesyan, B. Kopp, D. Schauberger, F. Darroudi, T. Grummt, G. Krupitza, R. Schulte-Hermann, S. Knasmüller (Wien, Leiden, Bad Elster)

_________
17.10.2006

12th Scientific Symposium of the Austrian Pharmacological Society (APHAR) Joint Meeting with the Austrian Society of Toxicology (ASTOX) POSTER PRESENTATIONS 23–25 November (→ Printversion)
(Preliminary program, subject to change)
POSTER Presentations
Posters will be on display for the entire period of the meeting (Thursday afternoon till Saturday noon). Presenting authors are requested to indicate their presence at their poster on the poster board (preferably during coffee breaks).
APHAR (Non-Clinical)
A7	A Site of Interaction between the Selectivity Filter and the Inner Vestibule of the Voltage-Gated Na⁺ Channel Touran Zarrabi*, B. Latzenhofer, M. Mille, E. Zebedin, K. Hilber, H. Todt (Wien)
A9	Duramycin Effects on hERG Potassium and Voltage-Gated Sodium Currents: A QT-Prolongation Risk? Eva Zebedin*, H. Pankevych, T. Zarrabi, B. Latzenhofer, M. Mille, H. Todt, M. Freissmuth, K. Hilber (Wien)
A10	Brain Lesions in Aortic Denervated vs. Sham-Operated Rats Dimitrios Kouvelas*, E. Amaniti, Ch. Pourzitaki, D. Kapoukranidou, J. Kalpidis, D. Vasilakos (Thessaloniki)
A16	The Signaling Mute hCMV Chemokine Receptor US28R129A Prevents Melanoma Growth Hannes Seidl*, H. Schaider, P. Quan, S. Frank, Z. Liu, M. Fukunaga, R. McDaid, H. Kerl, M. Herlyn, M. Waldhoer (Graz, Philadelphia)
APHAR (Clinical Section)
K1	No Immunomodulatory Effect of Fosfomycin in Experimental Endotoxemia in Humans Robert Sauermann*, C. Marsik, I. Steiner, K. Seir, T. Cvitko, M. Zeitlinger, B. Jilma, C. Joukhadar (Wien)
K2	Intravenous Administration of Clonidine Reduces Intraocular Pressure and Alters Ocular Blood Flow Günther Weigert*, H. Resch, A. Luksch, H.A. Reitsamer, G. Fuchsjäger-Mayrl, L. Schmetterer, G. Garhöfer (Wien)
K3	The Effects of Short Term Statin Pre-Treatment and Subsequent Low Dose Endotoxemia on Circulating Endothelial Progenitor Cells in Healthy Volunteers Alexander O. Spiel*, F.B. Mayr, J.M. Leitner, C. Firbas, W. Sieghart, B. Jilma (Wien)
K6	Effects of the Specific Interleukin-8 Inhibitor Reparixin on Endotoxin-Induced Inflammation Judith M. Leitner*, F.B. Mayr, A.O. Spiel, B. Steinlechner, B. Jilma (Wien)
K8	The Effects of Intravenous Histamine and Histamine Receptor Blockade on Ocular Blood Flow Katharina Karl*, H. Resch, G. Weigert, L. Schmetterer, G. Garhöfer (Wien)
K11	MicroPET Imaging with the β-Amyloid Probe [¹⁸F]FDDNP in a Transgenic Mouse Model of Alzheimer's Disease Oliver Langer*, C. Kuntner, T. Wanek, M. Bauer, M. Mandler, P. Angelberger, M. Müller, H. Kvaternik (Wien, Seibersdorf)
ASTOX
The presenters of ASTOX posters are requested to be present at their poster at the ASTOX Poster Session (Thursday 23 Nov, 13:30–14:00). Please make sure that you put up your poster before the session starts. The best ASTOX presentation (short communication or poster) will be selected to receive the Roche Prize (EUR 500), which will be awarded at the end of the Thursday afternoon session. Posters should remain on display throughout the entire meeting (i.e. until Saturday noon).
T1	Alkyl- and Aryl-Substituted Spin Traps: Free Radical Adduct Formation and Toxicity Studies Klaus Stolze*, N. Rohr-Udilova, B. Marian, B. Grasl-Kraupp, H. Nohl (Wien)
T4	Alterations of the Ras Pathway in Hepatocarcinogenesis: Species Comparison and Implications for Risk Assessment Doris Macheiner*, C. Rodgarkia-Dara, M. Grusch, H. Sutterlüty, W. Mikulits, H. Huber, R. Schulte-Hermann, B. Grasl-Kraupp (Wien)
T5	Linoleic Acid Hydroperoxides and the Induction of Antiapoptotic Genes in Cultured Hepatocarcinoma Cells Nataliya Rohr-Udilova*, S. Sagmeister, K. Stolze, H. Nohl, R. Schulte-Hermann, B. Grasl-Kraupp (Wien)
T8	*The Fusarium* Toxin Enniatin Exerts Cytotoxic Activities via Apotosis Induction** Rita Dornetshuber*, P. Heffeter, R. Kamyar, W. Berger, R. Lemmens-Gruber (Wien)
T9	Impact of Staining Procedures on the Results of the Micronucleus Assay with Exfoliated Cells as Biomarkers for Human Cancer Risk Armen Nersesyan*, M. Kundi, K. Atefie, R. Schulte-Hermann, S. Knasmüller (Wien)
L1	Hospital Waste Water: Health Risk for Human and Environment by Cytostatic Drug Emissions? Part I: Model Calculation and Chemical Monitoring M. Fuerhacker, S.N. Mahnik, K. Lenz, N. Weissenbacher, R.M. Mader, P. Krenn, S. Hann, G. Koellensperger, M. Uhl, S. Knasmüller, F. Ferk, Wilfried Bursch* (Wien)
L2	Hospital Waste Water: Health Risk for Human and Environment by Cytostatic Drug Emissions? Part II: Biological Monitoring (Genotoxicity Assays) and Risk Assessment F. Ferk, M. Uhl, M. Fuerhacker, S.N. Mahnik, K. Lenz, N. Weissenbacher, R.M. Mader, P. Krenn, S. Hann, G. Koellensperger, S. Knasmüller, Wilfried Bursch* (Wien)
L4	The Potential Antimutagenic and Antioxidant Effects of Maillard Reaction Products Used as "Natural Antibrowning" Agents S. Reichhold, K. Koschtnig, Karl-Heinz Wagner* (Wien)
L6	Use of Human-Derived Cell Lines for the Investigation of Dietary Factors which Affect DNA Stability Heike Winter*, B. Grasl-Kraupp, R. Schulte-Hermann, M. Grusch, W. Mikulits, V. Ehrlich, S. Knasmüller (Wien)
L7	DIMBOA and DIBOA, Two Naturally Occuring Benzoxazinoides, Cause Aneuploidy in a Human-Derived Liver Cell Line (HepG2) Christoph Buchmann*, A. Nersesyan, B. Kopp, D. Schauberger, F. Darroudi, T. Grummt, G. Krupitza, R. Schulte-Hermann, S. Knasmüller (Wien, Leiden, Bad Elster)